6-FLUOROPICOLINOYL CHLORIDE

6-FLUOROPICOLINOYL CHLORIDE - Names and Identifiers

Name	2-FLUORO-6-PYRIDINECARBONYL CHLORIDE
Synonyms	6-FLUOROPICOLINOYL CHLORIDE 6-FLUOROPYRIDINE-2-CARBONYL CHLORIDE 2-FLUOROPYRIDINE-6-CARBONYL CHLORIDE 2-FLUORO-6-PYRIDINECARBONYL CHLORIDE 2-Pyridinecarbonylchloride, 6-fluoro- 2-Pyridinecarbonyl chloride, 6-fluoro- (9CI)
CAS	64197-03-1

6-FLUOROPICOLINOYL CHLORIDE - Physico-chemical Properties

Molecular Formula	C6H3ClFNO
Molar Mass	159.55
Melting Point	48-50°C
Storage Condition	Room Temprature

6-FLUOROPICOLINOYL CHLORIDE - Risk and Safety

Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing.
HS Code	29339900

6-FLUOROPICOLINOYL CHLORIDE - Introduction

It is an organic compound with the chemical formula C6H4ClFO. The following are some relevant Properties, Uses, methods and safety information:

Nature:
-Appearance: Colorless to light yellow liquid.
-Boiling point: About 200 ℃.
-Melting point: About -4°C.
-Density: about 1.40g/cm³.
-Solubility: Soluble in most organic solvents.

Use: CHLORIDE is commonly used as a reagent in organic synthesis and can be used to synthesize various organic compounds.
-It is often used as intermediates or raw materials in drug synthesis, especially when researching and developing new drugs.

Method:
The preparation of CHLORIDE can generally be achieved through the following reaction pathways:
1. First, 2-fluoro-6-picolinic acid is treated with acid chloride.
2. Subsequently, the generated acid chlorine compound is chlorinated by a dehydrating agent (such as phosphorous chloride, stannous chloride, etc.).

Safety Information: CHLORIDE is an organochlorine compound. Contact with the skin or inhalation of its vapor may cause irritation, burns, allergic reactions and other adverse effects. Direct contact should be avoided.
-Wear appropriate protective equipment such as chemical protective gloves, goggles and protective clothing during use and handling.
-It should be used in a well-ventilated place and avoid mixing with oxidants, strong bases or strong acids.
-When storing, keep it in a sealed container, away from fire and high temperature.

Last Update：2024-04-09 21:01:54